학술논문

PLGA的降解行为及应用研究进展 / Research progress in degradation behavior and applications of PLGA
Document Type
Academic Journal
Source
中国塑料 / China Plastics. 38(1):92-99
Subject
聚乳酸-羟基乙酸共聚物
合成方法
聚集态结构
降解行为
poly(lactic-co-glycolic acid)
synthesis method
aggregated state structure
degradation behavior
Language
Chinese
ISSN
1001-9278
Abstract
从合成方法、聚集态结构、降解性能等方面对聚乳酸-羟基乙酸共聚物(PLGA)的研究进展进行了综述,并总结了合成方法和聚集态结构对PLGA降解性能的影响规律,同时简述了PLGA在药物控释、医用手术缝合线、骨组织工程支架等领域的应用情况.
This paper reviewed the research progress of poly(lactic-co-glycolic acid)(PLGA)from the aspects of synthe-sis method,aggregate structure,and degradation performance and summarized the influence of synthesis method and ag-gregate structure on the degradation of PLGA.Meanwhile,the application of PLGA for controlled drug release,medical surgical suture,and bone tissue engineering scaffold was briefly introduced.