학술논문
甲基强的松龙联合维生素D治疗对亚急性甲状腺炎患者甲状腺功能及炎性反应的影响 / Impact of Methylprednisolone Combined with Vitamin D on Thyroid Function and Inflammatory Response of Patients with Subacute Thyroiditis
Document Type
Academic Journal
Author
Source
临床医学工程 / Clinical Medical & Engineering. 31(2):181-182
Subject
Language
Chinese
ISSN
1674-4659
Abstract
目的 探讨甲基强的松龙联合维生素D治疗亚急性甲状腺炎的临床效果.方法 80 例亚急性甲状腺炎患者随机分为两组各 40 例.对照组采用甲基强的松龙治疗,研究组采用甲基强的松龙联合维生素D治疗.比较两组的甲状腺功能[游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)]、炎性指标[红细胞沉降率(ESR)、C反应蛋白(CRP)]以及不良反应.结果 治疗后,研究组的FT3 及FT4 水平均低于对照组,TSH水平高于对照组(P＜0.05).治疗后,研究组的ESR及CRP水平均低于对照组(P＜0.05).治疗期间,两组患者均未出现明显不良反应.结论 甲基强的松龙联合维生素D治疗亚急性甲状腺炎患者可显著改善其甲状腺功能,减轻炎性反应,安全性高.
Objective To explore the clinical effect of methylprednisolone combined with vitamin D in the treatment of subacute thyroiditis.Methods 80 patients with subacute thyroiditis were randomly divided into two groups,with 40 cases in each group.The control group was treated with methylprednisolone,and the study group was treated with methylprednisolone combined with vitamin D.The thyroid function[free triiodothyronine(FT3),free thyroxine(FT4),thyroid stimulating hormone(TSH)],inflammatory indicators[erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)]and adverse reactions were compared between the two groups.Results After treatment,the levels of FT3 and FT4 in the study group were lower than those in the control group,and the TSH level was higher than that in the control group(P<0.05).After treatment,the levels of ESR and CRP in the study group were lower than those in the control group(P<0.05).During the treatment,no obvious adverse reaction occurred in the two groups.Conclusions Methylprednisolone combined with vitamin D in the treatment of patients with subacute thyroiditis can obviously improve their thyroid function,reduce inflammatory response,and has high safety.
Objective To explore the clinical effect of methylprednisolone combined with vitamin D in the treatment of subacute thyroiditis.Methods 80 patients with subacute thyroiditis were randomly divided into two groups,with 40 cases in each group.The control group was treated with methylprednisolone,and the study group was treated with methylprednisolone combined with vitamin D.The thyroid function[free triiodothyronine(FT3),free thyroxine(FT4),thyroid stimulating hormone(TSH)],inflammatory indicators[erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)]and adverse reactions were compared between the two groups.Results After treatment,the levels of FT3 and FT4 in the study group were lower than those in the control group,and the TSH level was higher than that in the control group(P<0.05).After treatment,the levels of ESR and CRP in the study group were lower than those in the control group(P<0.05).During the treatment,no obvious adverse reaction occurred in the two groups.Conclusions Methylprednisolone combined with vitamin D in the treatment of patients with subacute thyroiditis can obviously improve their thyroid function,reduce inflammatory response,and has high safety.