학술논문
双源CT碘图评估肝硬化脾切除患者的肝脏血流动力学特点 / The assessment of hepatic hemodynamic characteristics in cirrhotic patients with splenectomy based on iodine map of dual-source CT
Document Type
Academic Journal
Author
朱永月; 周舟; 赵成利; 孙樱函; 周聪; 王道清; ZHU Yongyue; ZHOU Zhou; ZHAO Chengli; SUN Yinghan; ZHOU Cong; WANG Daoqing
Source
实用放射学杂志 / Journal of Practical Radiology. 40(2):302-305
Subject
Language
Chinese
ISSN
1002-1671
Abstract
目的 探讨双源CT(DSCT)碘图评估肝硬化脾切除患者的肝脏血流动力学特点.方法 选取24例肝硬化脾切除患者(研究组)、41例肝硬化脾未切除患者(肝硬化组)及32例肝脏正常者(对照组).在碘图上测量肝脏动、静脉期碘浓度(IC),并计算肝动脉碘分数(AIF)、门静脉碘浓度(PVIC).绘制受试者工作特征(ROC)曲线并记录曲线下面积(AUC),采用DeLong检验分析各参数的诊断效能.结果 研究组的动脉期IC、AIF显著升高,静脉期IC、PVIC显著降低(P<0.05);研究组和肝硬化组间参数独立诊断的AUC分别为0.735、0.992、0.943、0.994.结论 DSCT碘图有助于临床定量评估肝硬化脾切除患者的肝脏血流动力学特点,其中参数PVIC独立诊断的效能最优.
Objective To investigate the hepatic hemodynamic characteristics of cirrhotic patients with splenectomy using iodine map of dual-source computed tomography(DSCT).Methods Twenty-four cirrhotic patients with splenectomy were selected as a study group,41 cirrhotic patients without splenectomy as a cirrhosis group and other 32 patients with normal liver as a control group.The iodine concentration(IC)in hepatic arterial and venous phases was measured on the iodine map,and the arterial iodine fraction(AIF)and portal venous iodine concentration(PVIC)were calculated.Receiver operating characteristic(ROC)curves were plotted and the area under the curve(AUC)was recorded to evaluate the diagnostic efficacy of each parameter using the DeLong test.Results IC in arterial phase and AIF were significantly higher,and IC in venous phase and PVIC were significantly lower in study group(P<0.05).The AUC values of the four parameters between study group and cirrhosis group were 0.735,0.992,0.943,and 0.994,respectively.Conclusion DSCT iodine map is helpful for clinical quantitative assessment of hepatic hemodynamic characteristics in cirrhotic patients with splenectomy,and the PVIC has optimal independent diagnostic performance.
Objective To investigate the hepatic hemodynamic characteristics of cirrhotic patients with splenectomy using iodine map of dual-source computed tomography(DSCT).Methods Twenty-four cirrhotic patients with splenectomy were selected as a study group,41 cirrhotic patients without splenectomy as a cirrhosis group and other 32 patients with normal liver as a control group.The iodine concentration(IC)in hepatic arterial and venous phases was measured on the iodine map,and the arterial iodine fraction(AIF)and portal venous iodine concentration(PVIC)were calculated.Receiver operating characteristic(ROC)curves were plotted and the area under the curve(AUC)was recorded to evaluate the diagnostic efficacy of each parameter using the DeLong test.Results IC in arterial phase and AIF were significantly higher,and IC in venous phase and PVIC were significantly lower in study group(P<0.05).The AUC values of the four parameters between study group and cirrhosis group were 0.735,0.992,0.943,and 0.994,respectively.Conclusion DSCT iodine map is helpful for clinical quantitative assessment of hepatic hemodynamic characteristics in cirrhotic patients with splenectomy,and the PVIC has optimal independent diagnostic performance.