학술논문

左室射血分数对心力衰竭的诊断价值研究 / The Research of Diagnostic Value of Left Ventricular Ejection Fraction in Heart Failure
Document Type
Academic Journal
Source
中西医结合心脑血管病杂志 / Chinese Journal of Integrative Medicine on Cardio/Cerebrovascular Disease. (14):1593-1595
Subject
心力衰竭
左室射血分数
脑利钠肽前体
诊断试验
heart failure
left ventricular ejection fraction
N terminal pro brain natriuretic peptide
diagnosis test
Language
Chinese
ISSN
1672-1349
Abstract
目的:评价左室射血分数(LVEF)对心力衰竭的诊断价值。方法采用心力衰竭标志物N 末端脑利钠肽原(NT proBNP)作为金标准,用心脏超声仪 M型方法测定左室收缩功能(LVEF)值作为心力衰竭诊断试验指标,对134例心力衰竭住院患者分别进行盲法检测,并计算其敏感性、特异性、预测值与似然比。结果该项诊断试验敏感性和特异性分别为74.04%、73.33%,阳性预测值和阴性预测值分别为90.59%、44.90%,阳性似然比和阴性似然比分别为2.78、0.35。结论 LVEF对心力衰竭有一定的辅助诊断价值,但存在一定的误诊(27%)和漏诊(26%)。故不能单纯依赖 LVEF值进行心力衰竭诊断,而应结合临床症状和纽约心脏病协会(NYHA)心功能分级加以诊断。
Objective To evaluate the diagnostic value of left ventricular ejection fraction (LVEF)in heart failure.Methods N termi-nal pro brain natriuretic peptide (NT proBNP)was measured by 411 type electrochemistry luminescence instrument for gold standard and LVEF was measured by B ULTRASONIC with m type for diagnostic test indexs with blind method in 134 cases of pa-tients with heart failure.Then the value of their sensibility,specificity,predicted and likelihood ratio were counted respectively.Results The value of sensibility and specificity were 74.04% and 73.33%,respectively.The positive predicted value and nagtive predicted value were 90.59% and 44.90%,respectively.The value of positive likelihood ratio and nagtive likelihood ratio were 2.78 and 0.35 re-spectively in the diagnostic test.Conclusion LVEF had certain assist diagnostic value in clinical practice,but there were some misdi-agnosis (27%)and missing diagnosis(26%).LVEF could not diagnosed heart failure by alone.That clinical symptoms combined with NYNA cardiac function grading were necesary on diagnosis of heart failure.