학술논문
Community recommendations on cryoEM data archiving and validation
Document Type
Working Paper
Author
Kleywegt, Gerard J.; Adams, Paul D.; Butcher, Sarah J.; Lawson, Cathy; Rohou, Alexis; Rosenthal, Peter B.; Subramaniam, Sriram; Topf, Maya; Abbott, Sanja; Baldwin, Philip R.; Berrisford, John M.; Bricogne, Gérard; Choudhary, Preeti; Croll, Tristan I.; Danev, Radostin; Ganesan, Sai J.; Grant, Timothy; Gutmanas, Aleksandras; Henderson, Richard; Heymann, J. Bernard; Huiskonen, Juha T.; Istrate, Andrei; Kato, Takayuki; Lander, Gabriel C.; Lok, Shee-Mei; Ludtke, Steven J.; Murshudov, Garib N.; Pye, Ryan; Pintilie, Grigore D.; Richardson, Jane S.; Sachse, Carsten; Salih, Osman; Scheres, Sjors H. W.; Schroeder, Gunnar F.; Sorzano, Carlos Oscar S.; Stagg, Scott M.; Wang, Zhe; Warshamanage, Rangana; Westbrook, John D.; Winn, Martyn D.; Young, Jasmine Y.; Burley, Stephen K.; Hoch, Jeffrey C.; Kurisu, Genji; Morris, Kyle; Patwardhan, Ardan; Velankar, Sameer
Source
Subject
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Abstract
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 45 experts in data processing, model building and refinement, validation, and archiving of such structures. This report describes the workshop's motivation and history, the topics discussed, and consensus recommendations resulting from the workshop. Some challenges for future methods-development efforts in this area are also highlighted, as is the implementation to date of some of the recommendations.
Comment: Outcomes of a wwPDB/EMDB workshop on cryoEM data management, deposition and validation
Comment: Outcomes of a wwPDB/EMDB workshop on cryoEM data management, deposition and validation