학술논문

metaSPAdes: a new versatile de novo metagenomics assembler
Document Type
Working Paper
Source
Subject
Quantitative Biology - Genomics
Quantitative Biology - Quantitative Methods
Language
Abstract
While metagenomics has emerged as a technology of choice for analyzing bacterial populations, assembly of metagenomic data remains difficult thus stifling biological discoveries. metaSPAdes is a new assembler that addresses the challenge of metagenome analysis and capitalizes on computational ideas that proved to be useful in assemblies of single cells and highly polymorphic diploid genomes. We benchmark metaSPAdes against other state-of-the-art metagenome assemblers across diverse da-tasets and demonstrate that it results in high-quality assemblies.