학술논문

Self-supervised contrastive learning unveils cortical folding pattern linked to prematurity
Document Type
Working Paper
Source
MIDL 2024, Jul 2024, Paris, France
Subject
Quantitative Biology - Neurons and Cognition
Language
Abstract
Brain folding patterns have been reported to carry clinically relevant information. The brain folds mainly during the last trimester of pregnancy, and the process might be durably disturbed by preterm birth. Yet little is known about preterm-specific patterns. In this work, we train a self-supervised model (SimCLR) on the UKBioBank cohort (21070 adults) to represent the right superior temporal sulcus (STS) region and apply it to sulci images of 374 babies from the dHCP database, containing preterms and full-terms, and acquired at 40 weeks post-menstrual age. We find a lower variability in the preterm embeddings, supported by the identification of a knob pattern, missing in the extremely preterm population.