학술논문

Objective comparison of methods to decode anomalous diffusion
Document Type
Working Paper
Source
Subject
Physics - Data Analysis, Statistics and Probability
Condensed Matter - Soft Condensed Matter
Physics - Biological Physics
Quantitative Biology - Quantitative Methods
Language
Abstract
Deviations from Brownian motion leading to anomalous diffusion are ubiquitously found in transport dynamics, playing a crucial role in phenomena from quantum physics to life sciences. The detection and characterization of anomalous diffusion from the measurement of an individual trajectory are challenging tasks, which traditionally rely on calculating the mean squared displacement of the trajectory. However, this approach breaks down for cases of important practical interest, e.g., short or noisy trajectories, ensembles of heterogeneous trajectories, or non-ergodic processes. Recently, several new approaches have been proposed, mostly building on the ongoing machine-learning revolution. Aiming to perform an objective comparison of methods, we gathered the community and organized an open competition, the Anomalous Diffusion challenge (AnDi). Participating teams independently applied their own algorithms to a commonly-defined dataset including diverse conditions. Although no single method performed best across all scenarios, the results revealed clear differences between the various approaches, providing practical advice for users and a benchmark for developers.
Comment: 63 pages, 5 main figures, 1 table, 28 supplementary figures. Website: http://www.andi-challenge.org