부산대학교 도서관

Background. Our study evaluated the relationships between fasting plasma glucose (FPG) and the four 'Diabetes Factor' (DF) in the elderly lean Chinese population. The four diabetes factors included insulin resistance (IR), glucose effectiveness (GE), first- and second-phase insulin secretion (FPIS and SPIS). Methods. In total, 53 individuals with the same body mass index (22 kg/m^2) and age (65 years) were enrolled to eliminate the confounding factors. Pearson's correlation analysis was performed to assess the correlations between the four DFs and FPG. A general linear model was used to determine the differences in the percentage of change among the four factor slopes against the FPG. Results. Significant correlations between FPG and SPIS were observed in both male and female (P＜0.001). There is no significant association between FPG and FPIS, IR, and GE. Conclusion. In conclusion, the present study showed that in a group of healthy lean old subjects with the same age and body mass index, only SPIS is significantly related to FPG. The role of SPIS should be emphasized in the future.