부산대학교 도서관

The aim of this study was to investigate the presence of serum antibodies to different Leptospira serogroups in dogs with clinical signs of actue renal failure or icterus. Sera of fifty eight dogs were collected for antibody measurement with microscopic agglutination test and questionnaires of each dog were requested at the same time. The overall seropositive rate was 60.3% (35/58) and the most frequently present serogroups were Shermani (13/58) and lcterohaemorrhagiae (13/58). Fifteen dogs met the inclusion criteria for acute leptospirosis. Affected dogs were predominantly large-breed intact males. Ten of the infected dogs developed combined acute renal and hepatic disease, two with renal failure, and the rest with hepatic disease. The suspected infecting serogroups included 7 occurrences of Shermani, 4 of Bataviae, 2 of Australis, and 2 of Canicola. Common clinical signs included lethargy, anorexia and vomiting. Forteen dogs were treated conservatively (n=7, only three survived) or with hemodialysis (n=7, with 5 survived). For dogs with severe azotemia, treatment with hemodialysis appeared to improve prognosis.