부산대학교 도서관

Background: Impaired fasting glucose (IEG) is defined as fasting plasma glucose (FPG) 100 tug dl to 125 mg/dl which was set by American Diabetes Association (ADA). However, there is no suitable data to confirm IEG levels in Taiwan or Asian people. In the study, u e attempt to define suitable cutoff points for IFG in Taiwanese.. Method: We collected data from the people who visited our hospital for health examinations at least twice between 01/2002 and 07/2007. We excluded the people with a history of diabetes mellitus or the people with FPG≧126 mg/dl at first examination. There are 3330 subjects in the study. The criteria for the diagnosis of diabetes in the study are the people with a diagnosis of diabetes mellitus before second examination or FPG≧126 mg dl at second examination. We use the receiver operating characteristic (ROC) curve to calculate the cutoff point in IFG. Results: The mean duration between two health examinations are 930.68±430.08 days. According to the data of the ROC curve, the FPG cutoff point is 90 mg/dl. The area under ROC curve are 0.777±0.068. The sensitivity and specificity for the prediction of diabetes in the cutoff points are 0.691 and 0.733. Conclusion: The cutoff point of IFG is lower in Taiwan than the recommended value set by ADA. We suggest that the cutoff point for IFG should be reduced from 100 mg/dl to 90 mg/dl and that IFG should be redefined as fasting plasma glucose 90 to 125 tug dl in Taiwan.