부산대학교 도서관

Stroke is the second most common cause of death globally and is the leading cause of long-term disability. Stroke risk increases with age and life expectancy. Women tend to be older than men when they have a stroke. As a result, women suffer more strokes and die from more strokes in their lifetime. The complexity of stroke pathophysiology in women and their poorer stroke outcomes suggests that sex matters in stroke management. However, women were underrepresented in most randomized controlled trials. Hence, the data from major trials cannot be applicable in the clinical routine for the secondary prevention of stroke in women. Here, we review sex and gender differences in epidemiology, clinical features and outcomes, stroke types, risk factors, current recommendations for diagnosis and acute treatment, and primary and secondary prevention of stroke, with emphasis on recent evidence.