부산대학교 도서관

The whole world is now facing a very severe and treacherous challenge of a new coronavirus disease (COVID-19) with high morbidity and high mortality rate. The SARS-CoV-2 entered cells through angiotensin converting enzyme 2 (ACE2), which subsequently caused the secretion of cytokines and the production of a large number of reactive oxygen species (ROS), resulting in a strong inflammatory reaction that is harmful to life. Regularly moderate high-intensity exercise can increase ACE2 expression and help maintain normal physiological functions, and achieved anti-oxidation and anti-inflammatory effects. In addition, COVID-19 patients often suffer from lung tissue damage and acute respiratory distress syndrome. Moderate exercise can reduce inflammatory cytokines and stress hormones in the body to slow down the occurrence of cytokine storms. In addition, the activation of the chemotaxis and phagocytosis of immune cells moderate exercise may resist the invasion of SARS-CoV-2. Nowadays, the SARS-CoV-2 epidemic is threating the world, and fight against the mutant viruses will be the definite direction of epidemic prevention in the future. Through moderate and regular exercise to improve immunity may be one of the best strategies against SARS-CoV-2.