학술논문
500 MHz NMR characterization of synthetic bombesin and related peptides in DMSO‐d6by two‐dimensional techniques
Document Type
Article
Author
Source
FEBS Letters; September 1988, Vol. 237 Issue: 1-2 p85-90, 6p
Subject
Language
ISSN
00145793
Abstract
The proton NMR characterization of bombesin has been carried out at 500 MHz in DMSO‐d6using two‐dimensional homo‐ and 1H‐13C hetero‐correlated techniques. All resonances in the NMR spectra have been assigned and several coupling constants have been measured. The backbone JαCH‐NHcoupling constants have constant values that vary between 7.8 and 8.2 Hz and indicate an unfolded structure in DMSO‐d6. Discrepancies with data recently obtained at 300 MHz [(1987) Eur. J. Biochem. 168, 193–199] are discussed.