학술논문

Arteriolar C4d in IgA Nephropathy: A Cohort Study
Document Type
Article
Source
American Journal of Kidney Diseases; November 2020, Vol. 76 Issue: 5 p669-678, 10p
Subject
Language
ISSN
02726386; 15236838
Abstract
Glomerular C4d (C4dG) as an indicator of the lectin pathway of complement activation in immunoglobulin A nephropathy (IgAN) has been associated with more severe kidney damage. Recent studies have suggested that vascular lesions in IgAN biopsy specimens with complement deposition are also associated with disease progression. We aimed to study the clinical significance of arteriolar C4d (C4dA) in IgAN kidney biopsy tissue.