학술논문
Engrafted Donor-Derived Clonal Hematopoiesis after Allogenic Hematopoietic Cell Transplantation is Associated with Chronic Graft-versus-Host Disease Requiring Immunosuppressive Therapy, but no Adverse Impact on Overall Survival or Relapse
Document Type
Article
Author
Source
Transplantation and Cellular Therapy; August 2021, Vol. 27 Issue: 8 p662.e1-662.e9, 9p
Subject
Language
ISSN
26666375; 26666367
Abstract
•Clonal hematopoiesis (CH) mutations may be transferred from donor to recipient at the time of hematopoietic cell transplantation.•Engrafted donor-derived CH is associated with chronic graft-versus-host disease (cGVHD) necessitating immunosuppressive therapy (IST).•Patients with engrafted donor-derived CH and cGVHD are less likely to discontinue IST.