학술논문
Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial
Document Type
Article
Author
Chappell, Lucy C; Brocklehurst, Peter; Green, Marcus E; Hunter, Rachael; Hardy, Pollyanna; Juszczak, Edmund; Linsell, Louise; Chiocchia, Virginia; Greenland, Melanie; Placzek, Anna; Townend, John; Marlow, Neil; Sandall, Jane; Shennan, Andrew; Agarwal, Umber; Ahmed, Irshad; Ajay, Bini; Alfirevic, Zarko; Arya, Rita; Bambridge, Gabrielle; Bamfo, Jacqueline; Basak, Sambita; Bowler, Ursula; Cameron, Helen; Churchill, David; Cresswell, Janet; Crosfill, Fiona; Denbow, Mark; Dey, Madhuchanda; Everden, Caroline; Ficquet, Jo; Gajewska-Knapik, Katarzyna; Ganapathy, Ramesh; Garrett, Angela; Girling, Joanna; Gornall, Adam; Harding, Kate; Hendy, Eleanor; Howard, Richard; James, Mark; Johnson, Antoinette; Kemp, Michelle; Khalil, Asma; Khan, Rehan; Khan, Rahila; Knox, Ellen; Margarit, Lavinia; Marsden, Philippa; McIntyre, Karen; Myers, Jenny; Nugent, Justine; Rao, Sanjay; Robinson, Zoey; Robson, Stephen; Rushby, Pauline; Scholz, Laura; Shahin, Mohamed; Sharma, Bhavna; Simpson, Nigel; Singh, Natasha; Sparkes, Jenie; Stone, Sophia; Subair, Seni; Tan, Bee; Thakur, Vidya; Thamban, Sujatha; Thornton, Jim; Thornton, Jim; Tohill, Sue; Tsoi, Elly; Tuffnell, Derek; Waterstone, Mark; Waugh, Jason; Wiesender, Cornelia; Wu, Pensee
Source
The Lancet; September-October 2019, Vol. 394 Issue: 10204 p1181-1190, 10p
Subject
Language
ISSN
01406736; 1474547X
Abstract
In women with late preterm pre-eclampsia, the optimal time to initiate delivery is unclear because limitation of maternal disease progression needs to be balanced against infant complications. The aim of this trial was to determine whether planned earlier initiation of delivery reduces maternal adverse outcomes without substantial worsening of neonatal or infant outcomes, compared with expectant management (usual care) in women with late preterm pre-eclampsia.