학술논문
Diagnostic performances and therapeutic impact of the Unyvero Implant and Tissue Infection multiplex PCR in periprosthetic joint infections
Document Type
Article
Author
Source
Future Microbiology; July 2023, Vol. 18 Issue: 11 p723-734, 12p
Subject
Language
ISSN
17460913; 17460921
Abstract
Aim:We evaluated the diagnostic performances of Unyvero Implant and Tissue Infection multiplex PCR (mPCR) (Curetis) and the clinical impact of this PCR on therapeutic decisions. Materials & methods:A mPCR was performed on 33 joint fluids in addition to standard culture. A group of experts analyzed a posteriorithe impact of the mPCR in the patient management. Results:The rate of concordance with culture was 74% (20/27). The sensitivity of the PCR was 59% and the specificity 90%. Clinicians would have started an appropriate treatment sooner for six patients (from 2 to 22 days earlier). Conclusion:The PCR would improve the management of 22% of the patients. For other patients, mPCR results have to be completed with the culture.