학술논문
Relative Prognostic Value of Self-Reported Adherence and Plasma Nnrti/Pi Concentrations to Predict Virological Rebound in Patients Initially Responding to Haart
Document Type
Article
Author
Antinori, Andrea; Cozzi-Lepri, Alessandro; Ammassari, Adriana; Trotta, Maria Paola; Nauwelaers, David; Hoetelmans, Richard; Murri, Rita; Melzi, Sara; Narciso, Pasquale; Nasta, Paola; Zaccarelli, Mauro; Santopadre, Paola; Vecchiet, Jacopo; Izzo, Crescenzo Maria; Monforte, Antonella d'Arminio; Tirelli, U; Nasti, G; Carosi, G; Nasta, P; Manconi, PE; Piano, P; Pizzigallo, E; Dalessandro, M; Vecchiet, J; Mazzotta, F; Caputo, S Lo; Soscia, F; Tacconi, L; Scasso, A; Vincenti, A; Scalzini, A; Fibbia, GC; Moroni, M; Manforte, A d'Arminio; Melzi, S; Esposito, R; Mussini, C; Piazza, M; Abrescia, N; Izzo, MC; Marco, M De; Manzillo, E; Nappa, S; Alberici, F; Sisti, M; Baldelli, F; Loso, K; Mele, P; Acinapura, R; Ammassari, A; Antinori, A; Antonucci, G; Ciardi, M; Delia, S; Longis, P De; D'Offizi, G; Ippolito, G; Lichtner, M; Marconi, P; Murri, R; Narciso, P; Noto, P; Petrosillo, N; Pezzotti, P; Santopadre, P; Trotta, MP; Vullo, V; Zaccarelli, M; Caramello, P; Orofino, GC; Cozzi-Lepri, A; Baltimore, MD.; Wu, AW
Source
Antiviral Therapy; February 2004, Vol. 9 Issue: 2 p291-296, 6p
Subject
Language
ISSN
13596535
Abstract
We studied the predictive value of self-reported adherence and plasma drug concentrations on virological rebound to HAART. Among 238 participants in the AdICoNA study who had viral load =500 copies/ml, 42 (17.6%) experienced virological rebound by 96 weeks. Both self-reported non-adherence and sub-optimal concentration were independently associated with a higher risk of virological rebound.