학술논문
SYNTHESIS AND REACTIONS OF SOME 2-THIENYL- AND 2-THENOYL-DERIVATIVES OF THIAZOLE AND THIADIAZOLINE AND THEIR SELENIUM ANALOGS
Document Type
Article
Source
Phosphorus, Sulfur, and Silicon and the Related Elements; December 1988, Vol. 40 Issue: 3 p243-249, 7p
Subject
Language
ISSN
10426507; 15635325
Abstract
2-(Thiocyanatoacetyl)thiophene 2 and its selenium analog 3 couple with diazotized anilines and yield 3-aryl-2-imino-5-(2-thenoyl)-2,3-dihydro-1,3,4-thiadiazoles 6 and 3-aryl-2-imino-5-(2-thenoyl)-2,3-dihydro-1,3,4-selenadiazoles 7 respectively. The reactions of both 6 and 7 with nitrous acid, acetic anhydride and benzoyl chloride are described. Azo coupling of 2-amino-4-(2-thienyl)thiazole 17 and its selenazole analog 18 with diazotized anilines yielded the arylazo derivatives 19 and 20 respectively. Reaction of the hydrazidoyl bromide 16 with potassium thiocyanate, potassium selenocyanate, thiourea and selenourea yields 6, 7, 19, and 20 respectively.