학술논문
Evaluation of the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma (SOURCE): a randomised, placebo-controlled, phase 3 study
Document Type
Article
Author
Wechsler, Michael E; Menzies-Gow, Andrew; Brightling, Christopher E; Kuna, Piotr; Korn, Stephanie; Welte, Tobias; Griffiths, Janet M; Sałapa, Kinga; Hellqvist, Åsa; Almqvist, Gun; Lal, Harbans; Kaur, Primal; Skärby, Tor; Colice, Gene; Cambursano, Victor H; Fernandez, Marcelo J; Scherbovsky, Fernando D; Yanez, Anahi; Tolcachier, Alberto J; Stok, Ana M; Verra, Fernando J B; Korn, Stephanie; Forster, Karin; Rolke, Mathias; Ludwig-Sengpiel, Andrea; Schmoller, Tibor; Schmidt, Olaf; Milger-Kneidinger, Katrin; Hoffmann, Martin; Temme, Hilke; Linnhoff, Anneliese; Welte, Tobias; Kirschner, Joachim; Kuna, Piotr; Rewerska, Barbara; Pisarczyk-Bogacka, Ewa; Haak Lee, Sang; Jae Lee, Byung; Park, Heung-Woo; Park, Jung-Won; Young Lee, Sook; Sook Cho, You; Ho Lee, Kwan; Bavbek, Sevim; Gemicioglu, Bilun; Ediger, Dane; Koca Kalkan, Ilkay; Hanta, Ismail; Yorgancioglu, Arzu; DytyatkovsKa, Yevgeniya; Mostovoy, Yuriy M; Lebed, Kyrylo; Yakovenko, Oleh; Bernstein, David I; Tillinghast, Jeffrey P; Que, Loretta; Madison, Jan; Rambasek, Todd; Shenoy, Kartik; Thompson, Charles A; Chappel, Christopher M; Hudes, Golda; Sorial, Ehab; Kureishy, Shahrukh A; Rehman, Syed M; Lugogo, Njira; Gonzalez, Erika G; Umeh, Fred C; Boren, Eric J; Sigmon, Jason; Ismail, Hummayun; Mohan, Arjun; Bansal, Sandeep; Kaelin, Thomas D
Source
The Lancet Respiratory Medicine; July 2022, Vol. 10 Issue: 7 p650-660, 11p
Subject
Language
ISSN
22132600; 22132619
Abstract
Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin. SOURCE evaluated the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma.