학술논문
Regio- and Enantioselective Iridium-Catalyzed Amination of Alkyl-Substituted Allylic Acetates with Secondary Amines
Document Type
Article
Author
Source
Organic Letters; January 2022, Vol. 24 Issue: 1 p441-445, 5p
Subject
Language
ISSN
15237060; 15237052
Abstract
Robust air-stable cyclometalated π-allyliridium C,O-benzoates modified by (S)-tol-BINAP catalyze the reaction of secondary aliphatic amines with racemic alkyl-substituted allylic acetates to furnish products of allylic amination with high levels of enantioselectivity. Complete branched regioselectivities were observed despite the formation of more highly substituted C–N bonds.