학술논문
Diagnostic evaluation of paediatric autoimmune lymphoproliferative immunodeficiencies (ALPID): a prospective cohort study
Document Type
Article
Author
Hägele, Pauline; Staus, Paulina; Scheible, Raphael; Uhlmann, Annette; Heeg, Maximilian; Klemann, Christian; Maccari, Maria Elena; Ritterbusch, Henrike; Armstrong, Martin; Cutcutache, Ioana; Elliott, Katherine S; von Bernuth, Horst; Leahy, Timothy Ronan; Leyh, Jörg; Holzinger, Dirk; Lehmberg, Kai; Svec, Peter; Masjosthusmann, Katja; Hambleton, Sophie; Jakob, Marcus; Sparber-Sauer, Monika; Kager, Leo; Puzik, Alexander; Wolkewitz, Martin; Lorenz, Myriam Ricarda; Schwarz, Klaus; Speckmann, Carsten; Rensing-Ehl, Anne; Ehl, Stephan; Abinun, Mario; Abrahamsen, Tore; Albert, Michael; Almalky, Mohamed; Altaf, Sadaf; Babayeva, Royala; Bakhtiar, Shahrzad; Baris, Safa; Baumann, Ulrich; Becker, Martina; Berger, Thomas; Biebl, Ariane; Bielack, Stefan; Biskup, Saskia; Bismarck, Philipp; Bode, Sebastian; Borchers, Regine; Boztug, Carl Friedrich; Brockmann, Knut; Bruwier, Annelyse; Buchholz, Bernd; Cant, Andrew; Castro, Carla N; Classen, Carl; Claviez, Alexander; Crazzolara, Roman; Cuntz, Franziska; Dąbrowska-Leonik, Nel; Derichs, Ute; Dückers, Gregor; Eberl, Wolfgang; Ebetsberger-Dachs, Georg; Erlacher, Miriam; Fabre, Alexandre; Faletti, Laura; Farmand, Susan; Figueiredo, Antonio; Fischer, Marco; Flaadt, Tim; Full, Hermann; Gambineri, Eleonora; Girschick, Hermann; Goldacker, Sigune; Grimbacher, Bodo; Groß, Miriam; Gruhn, Andrew J; Gungoren, Ezgi; Haberfellner, Florian; Hague, Rosie; Hauch, Holger; Hauck, Fabian; Heine, Sabine; Holzinger, Dirk; Huisman, Elise; Jakovljevic, Gordana; James, Beki; Janda, Ales; Janda, Małgorzata; Jones, Neil; Kaiser-Labusch, Petra; Kentouche, Karim; Knight, Julian; Knirsch, Stephanie; Kontny, Udo; Körholz, Julia; Krenn, Ezgi Yalcin; Kuehnle, Ingrid; Kühne, Thomas; Lee-Dimroth, Jae-Yun; Lehmann, Hartwig; Leipold, Michael H.; Meinhardt, Andrea; Mönkemöller, Kirsten; Morbach, Henner; Mücke, Urs; Nathrath, Michaela; Naumann-Bartsch, Nora; Neth, Olaf; Niemeyer, Charlotte; Olbrich, Peter; Ostró, Róbert; Owens, Stephen; Pac, Malgorzata; Pachlopnik Schmid, Rita; Page, Markus G.; Pekrun, Arnulf; Prader, Seraina; Proietti, Michele; Puzik, Alexander; Rajacic, Nada; Rothoeft, Tobias; Ryan, Freimut H.; Salou, Sarah; Salzer, Elisabeth; Savic, Sinisa; Schilling, Antonio E.; Schmid, Jana; Schönberger, Stefan; Schuetz, Catharina; Schuez-Havupalo, Tore G.; Schulte, Björn; Schulz, Ansgar; Schuster, Volker; Seidel, Markus; Siepermann, Kathrin; Smisek, Petr; Soomann, Maarja; Stiefel, Martina; Storck, Simone; Strahm, Brigitte; Streiter, Elise J; Teltschik, Charlotte M.; Thalhammer, Julian; Tippelt, Stephan; Toskov, Vasil; Trück, Johannes; Vieth, Simon; Wegehaupt, Oliver; Wiesel, Thomas
Source
The Lancet Haematology; February 2024, Vol. 11 Issue: 2 pe114-e126, 13p
Subject
Language
ISSN
23523026
Abstract
Lymphoproliferation and autoimmune cytopenias characterise autoimmune lymphoproliferative syndrome. Other conditions sharing these manifestations have been termed autoimmune lymphoproliferative syndrome-like diseases, although they are frequently more severe. The aim of this study was to define the genetic, clinical, and immunological features of these disorders to improve their diagnostic classification.