학술논문
Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
Document Type
Article
Author
Garvey, W Timothy; Frias, Juan P; Jastreboff, Ania M; le Roux, Carel W; Sattar, Naveed; Aizenberg, Diego; Mao, Huzhang; Zhang, Shuyu; Ahmad, Nadia N; Bunck, Mathijs C; Benabbad, Imane; Zhang, Xiaotian M; Abalos, Franklin H.; Manghi, Federico C.P.; Zaidman, Cesar J.; Vico, Marisa L.; Aizenberg, Diego; Costanzo, Pablo R.; Serra, Leonardo P.; MacKinnon, Ignacio J.; Hissa, Miguel N.; Vidotti, Maria H.; Kerr Saraiva, Jose F.; Alves, Breno B.; Franco, Denise R.; Moratto, Otavio; Murthy, Sreenivasa; Goyal, Ghanshyam; Yamasaki, Yoshimitsu; Sato, Nobuyuki; Inoue, Satoshi; Asakura, Taro; Shestakova, Marina; Khaykina, Elena; Troshina, Ekaterina; Vorokhobina, Natalia; Ametov, Alexander; Tu, Shih-Te; Yang, Chwen-Yi; Lee, I-Te; Huang, Chien-Ning; Ou, Horng-Yih; Freeman, George; Machineni, Sriram; Klein, Klara; Sultan, Senan; Parsa, Alan; Otero-Martinez, Juan; Gonzalez, Alex; Bhargava, Anuj; Brian, Susan; Ince, Carlos; Plantholt, Stephen; Cole, Jeremy; Lacour, Audrey; Vega, Damaris; de Souza, Jose; Rohlf, Jane L.; St. John, Roy C.; Horowitz, Barry; Audish, Hanid; Galindo, Rodolfo; Umpiperrez, Guillermo; Ard, Jamy; Curtis, Brian; Garvey, William T.; Fraser, Neil J.; Mandry, Jose; Mohseni, Rizwana; Mayfield, Ronald; Powell, Talessa; Vance, Carl; Ong, Stephen; Lewy-Alterbaum, Ana L.; Murray, Alexander; Al-Karadsheh, Amer; Yacoub, Tamer; Roberts, Kevin; Fried, David L.; Rosenstock, Julio; Pulla, Bharathi; Bode, Bruce; Frias, Juan; Klaff, Leslie; Brazg, Ronald; Van, Joanna; Tan, Anjanette; Briskin, Toby; Rhee, Margaret; Chaicha-Brom, Tira; Hartley, Paul A.; Nunez, Lazaro; Cortes-Maisonet, Gregorio; Soucie, Gary; Hsia, Stanley; Jones, Thomas
Source
The Lancet; 20230101, Issue: Preprints
Subject
Language
ISSN
01406736; 1474547X
Abstract
Weight reduction is essential for improving health outcomes in people with obesity and type 2 diabetes. We assessed the efficacy and safety of tirzepatide, a glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, versus placebo, for weight management in people living with obesity and type 2 diabetes.