학술논문
Effects of Long-Term Denosumab on Bone Histomorphometry and Mineralization in Women With Postmenopausal Osteoporosis
Document Type
Article
Author
Source
The Journal of Clinical Endocrinology & Metabolism; July 2018, Vol. 103 Issue: 7 p2498-2509, 12p
Subject
Language
ISSN
0021972X; 19457197
Abstract
After up to 10 years of denosumab therapy, iliac bone biopsies from postmenopausal women showed normal histology, reduced bone remodeling, and increased matrix mineralization that plateaued by year 5.