학술논문
Inclusion of organ movements in IMRT treatment planning via inverse planning based on probability distributions
Document Type
Article
Author
Source
Physics in Medicine and Biology; September 7, 2004, Vol. 49 Issue: 17 p4005-4029, 25p
Subject
Language
ISSN
00319155; 13616560
Abstract
In this paper, we investigate an off-line strategy to incorporate inter-fraction organ motion in IMRT treatment planning. It was suggested that inverse planning could be based on a probability distribution of patient geometries instead of a single snap shot. However, this concept is connected to two intrinsic problems: first, this probability distribution has to be estimated from only a few images; and second, the distribution is only sparsely sampled over the treatment course due to a finite number of fractions. In the current work, we develop new concepts of inverse planning which account for these two problems.