학술논문
Detection of Tumor Epidermal Growth Factor Receptor Pathway Dependence by Serum Mass Spectrometry in Cancer Patients.
Document Type
Article
Author
Source
Cancer Epidemiology, Biomarkers & Prevention; Feb2010, Vol. 19 Issue 2, p358-365, 8p, 3 Charts, 2 Graphs
Subject
Language
ISSN
10559965
Abstract
The article presents research which examined the use of serum mass spectrometry in detecting tumor epidermal growth factor receptor (EGFR) pathway dependence in cancer patients. The researchers analyzed pretreatment plasma or serum from 230 patients who have undergone chemotherapy or treatment with cetuximab. They found that serum proteomic profiling is effective in diagnosing significant tumor dependence on the pathway of EGFR in people who are suffering from non-small cell lung cancer.