학술논문
Induced hypothermia in patients with septic shock and respiratory failure (CASS): a randomised, controlled, open-label trial
Document Type
Article
Author
Itenov, Theis Skovsgaard; Johansen, Maria Egede; Bestle, Morten; Thormar, Katrin; Hein, Lars; Gyldensted, Louise; Lindhardt, Anne; Christensen, Henrik; Estrup, Stine; Pedersen, Henrik Planck; Harmon, Matthew; Soni, Uday Kant; Perez-Protto, Silvia; Wesche, Nicolai; Skram, Ulrik; Petersen, John Asger; Mohr, Thomas; Waldau, Tina; Poulsen, Lone Musaeus; Strange, Ditte; Juffermans, Nicole P; Sessler, Daniel I; Tønnesen, Else; Møller, Kirsten; Kristensen, Dennis Karsten; Cozzi-Lepri, Alessandro; Lundgren, Jens D; Jensen, Jens-Ulrik; Jensen, Jens-Ulrik Stæhr; Itenov, Theis Skovsgaard; Johansen, Maria Egede; Lundgren, Jens; Tønnesen, Else; Bestle, Morten; Lindhardt, Anne; Christensen, Henrik; Planck Pedersen, Henrik; Poulsen, Lone Musaeus; Cozzi-Lepri, Alessandro; Illkjær, Susanne; Soni, Uday Kant; Møller, Kirsten; Juffermans, Nicole P; Sessler, Daniel I; Mohr, Thomas; Masur, Henry; Torp-Pedersen, Christian; Copas, Andrew; Nielsen, Birgit Riis; Kristensen, Dennis Karsten; Grarup, Jesper; Hansen, Jette; Nielsen, Kim; Valbjørn, Lone; Lauritzen, Sanne; Kold, Tina; Grundahl, Kathrine; Hein, Lars; Rasmussen, Rikke Hein; Wesche, Nikolaj; Blom, Hasse; Jensen, Peer Eske; Galle, Tina; Thaarslund, Bente; Skandov, Camilla; Langholz, Iben; Skram, Ulrik; Berthelsen, Rasmus Ehrenfried; Kjær, Dorthe; Uldbjerg, Merete; Lipsius, Lily; Gyldensted, Louise; Engsig, Magaly; Helsted, Rikke; Andersen, Birgitte; Nygaard, Eigil; Strande, Søren; Bangash, Aimal Khan; Waldau, Tina; Søe-Jensen, Peter; Tousi, Hamid; Tangager, Malene; Hagi-Pedersen, Daniel; Gatz, Rainer Karl-Heinz; Engen, Marte Kaasen; Wamberg, Christian Åge; Westergaard, Bo; Harmon, Matthew; Thormar, Katrin; Stoktoft, Stine; Scherwin, Rebecca; Bærentzen, Finn; Lauritzen, Marlene; Pott, Frank; Bruun, Christina; Meyhoff, Christian; Strange, Ditte Gry; Palmqvist, Dorthe Fris; Hemmingsen, Claus; Gärtner, Rune; Petersen, John Asger; Jung, Kai Dieter; La Porte, Louise; Viuf, Mette; Troglauer, Johannes; Borovnjak, Silva; Strandkjær, Nina; Bretlau, Claus; Hansen, Marianna; Zaulich, Lea Kielsgaard; Overgaard, Christian; Bergenholtz, Katja; Jansen, Tejs; Bæk-Jensen, Mette Astrup; Detlefsen, Monika; Albrechtsen, Tannie Lund; Sode, Birgitte Margareta; Boesen, Hans Christian; Thostrup, Maria; Estrup, Stine; Andersen, Torben Mogens; Kjelsteen, Katrine; Winther Kjær, Cilia Klara; Haunstrup, Elsebeth; Christensen, Ole; Spliid, Lone; Rasmussen, Birgitte; Jejlskov, Henriette; Borchorst, Søren; Abdel-Wahab, Akil Walli Raad; Brysting, Marianne; Victor, Jette; Stensbirk, Anette; Bjerregaard, Karen; Poulsen, Anne; Roed, Annette Brix; Bech, Bianca; Perez-Protto, Silvia; Yilmaz, Oguz; Ahuja, Sanchit; Suleiman, Iman; Iglesias, Rodrigo; Breum, Olena
Source
The Lancet Respiratory Medicine; March 2018, Vol. 6 Issue: 3 p183-192, 10p
Subject
Language
ISSN
22132600; 22132619
Abstract
Animal models of serious infection suggest that 24 h of induced hypothermia improves circulatory and respiratory function and reduces mortality. We tested the hypothesis that a reduction of core temperature to 32–34°C attenuates organ dysfunction and reduces mortality in ventilator-dependent patients with septic shock.