학술논문
Estrogen Metabolism and Mammographic Density in Postmenopausal Women: A Cross-Sectional Study.
Document Type
Article
Author
Source
Cancer Epidemiology, Biomarkers & Prevention; Sep2012, Vol. 21 Issue 9, p1582-1591, 10p
Subject
Language
ISSN
10559965
Abstract
The article discusses a cross-sectional study of postmenopausal women to examine if estrogens, estrogen metabolites or estrogen metabolism (EM) are associated with mammographic density (MD). The urinary EM was measured using a liquid chromatography-tandem mass spectromety (LC-MS/MS) assay which identified 2 patterns of EM associated with reduced postmenopausal breast cancer risk. It suggests that increased hydroxylation of parent estrogens can protect against breast cancer.