학술논문
Anaesthetic depth and complications after major surgery: an international, randomised controlled trial
Document Type
Article
Author
Short, Timothy G; Campbell, Douglas; Frampton, Christopher; Chan, Matthew T V; Myles, Paul S; Corcoran, Tomás B; Sessler, Daniel I; Mills, Gary H; Cata, Juan P; Painter, Thomas; Byrne, Kelly; Han, Ruquan; Chu, Mandy H M; McAllister, Davina J; Leslie, Kate; Shulman, M; Wallace, S; Farrington, C; Gallagher, W; Ditoro, A; Peyton, P; Baulch, S; Dalyell, A; Sidiropoulos, S; Reynolds, J; Rowley, J; Tan, N; McCallum, D; O'Loughlin, E; Wong, S; Owen, K; Sim, I-K; Glazov, L; Coutts, P; Pushpanathan, M; Findlay, V; Paech, M; Cavill, D; Chuan, A; Pope, L; Lucas, J; Robinson, B; Millard, A; Allen, S; Allen, M; McKeown, S; Sivalingam, P; Wilkes, T; Jowett, C; Kearney, A; Bennett, M; Favero, J-P; Sawhney, S; Drummond, K; Osborn, S; Wing, A; Taylor, J; Edwards, M; Reynolds, H; Town, C; Terblanche, N; Challis, M; Seale, R; Button, K; Cotter, R; Stewart, M; Zingerle, N; Hannon, S; Middleton, D; Edgley, C; March, S; McCulloch, T; Wong, G; Jeong, S; Connell, K; Kramer, K; Henderson, G; Ward, V; Buller, Y; Hird, N; Scott, D; Evered, L; Snyder, G; Silbert, B; Corcoran, P; Fitzgerald, E; Said, S; Watson, A; Baby, D; Bolsin, S; Marriott, A; Ives, K; Wakefeld, B-J; Jeffreys, A; Bates, S; Halliwell, R; Elliott, D; Cope, L; Paranthoiene, R; Peng, P; Liu, X; Zhou, X; Jin, X; Liu, H; An, L; Cui, W; Zhang, L; Jia, B; Fang, J; Koo, E; Lo, E; Fung, B; Tsang, M; Lam, L; Pang, E; Lau, V; Choi, G; Tsang, M; Fung, B; Kwok, R; Yau, K; Cheng, B; Lam, C; Lee, E; Buggy, D; Keane, H; Byrne, K; Connolly, C; Ali, M; Cervantes, A; Kumar, K; Dandy, S; Ritchie, L; Kennedy, R; McKellow, M; Read, C; France, D; Truong, H; Chapman, C; Walker, S; Olliff, S; Houston, H; Scott, M; Minchin, I; Moniwa, A; McAlpine, J; Chaddock, M; Gray, L; Czepanski, C; Vinish, S; Buehner, U; Williams, E; Zhou, C; Goodman, L; Bermaat, J; Mans, G; Garden, A; Franks, R; Deiterle, J; Barrett, J; Roubos, S; van Lier, F; Verbrugge, S; Kalkman, C; Dieleman, J; Verdam-Veldkamp, J; van Kampen, A; Pai, A; Sevillano, A; Yeung, J; Melody, T; Atterbury, K; Hough, M; Dukes, S; Williams, S; Milan, Z; Kunst, G; Bhatia, K; MacNab, W; Weaver, E; Moulding, R; Doble, P; Klepsch, P; Self, J; Howes, T; Rees, B; Faulkner, B; Blackburn, J; Crombie, N; Cooper, L; Nair, A; Bell, G; Longfellow, R; Nicholas, C; Garratt, T; Pollard, M; Brown, G; Morrison, G; Lang, A; Dawson, H; MacDonald, M; Martin, T; Niebrzegowska, E; Dias, P; Rao Baikady, R; Jhanji, S; Siddaiah, N; Bird, L; Mittal, R; Nalawaya, P; Sonksen, J; Gidda, R; Wrench, I; Craw, N; Pippard, L; Davies, S; Wright, M; Turan, M; Maheshwari, K; Cohen, B; Saasouh, W; Singh, P; Govindarajan, S; Cuko, E; Marcano, F; Babazade, R; Leung, S; Raza, S; Reville, E; Hanline, C; Ayad, S; Buttar, M; Akhtar, Z; Niazi, A; Saha, P; Morris, A; Lokhande, C; Hassan, M; Honar, H; Bairacharya, G; Saxon, J; Chelnick, D; Carlson, R; Ruiz, J; Wilks, J; Williams, W; Dangler, L; Ifeanyi-Pillette, I; Suarez, J; Erfe, R; Perez, A; Veselis, R; Yang, G; Mehta, M; Pryor, K; Rubin, L; Malhotra, J; Steinkamp, M; Cooke, F; Friedlander, R
Source
The Lancet; November 2019, Vol. 394 Issue: 10212 p1907-1914, 8p
Subject
Language
ISSN
01406736; 1474547X
Abstract
An association between increasing anaesthetic depth and decreased postoperative survival has been shown in observational studies; however, evidence from randomised controlled trials is lacking. Our aim was to compare all-cause 1-year mortality in older patients having major surgery and randomly assigned to light or deep general anaesthesia.