학술논문
Age-specific breast and ovarian cancer risks associated with germline BRCA1or BRCA2pathogenic variants – an Asian study of 572 families
Document Type
Article
Author
Ho, Weang-Kee; Hassan, Tiara; Yoon, Sook-Yee; Yang, Xin; Lim, Joanna M.C.; Binte Ishak, Nur Diana; Ho, Peh Joo; Wijaya, Eldarina A.; Pei-Sze Ng, Patsy; Luccarini, Craig; Allen, Jamie; Tai, Mei-Chee; Chiang, Jianbang; Zhang, Zewen; See, Mee-Hoong; Thong, Meow-Keong; Woo, Yin-Ling; Dunning, Alison M.; Hartman, Mikael; Yip, Cheng-Har; Mohd Taib, Nur Aishah; Easton, Douglas F.; Li, Jingmei; Ngeow, Joanne; Antoniou, Antonis C.; Teo, Soo-Hwang
Source
The Lancet Regional Health - Western Pacific; 20240101, Issue: Preprints
Subject
Language
ISSN
26666065
Abstract
Clinical management of Asian BRCA1and BRCA2pathogenic variants (PV) carriers remains challenging due to imprecise age-specific breast (BC) and ovarian cancer (OC) risks estimates. We aimed to refine these estimates using six multi-ethnic studies in Asia.