학술논문
Tyrosine kinase-2gene polymorphisms are associated with ulcerative colitis and Crohn's disease in Turkish Population
Document Type
Article
Author
Source
Clinics and Research in Hepatology and Gastroenterology; September 2015, Vol. 39 Issue: 4 p489-498, 10p
Subject
Language
ISSN
22107401
Abstract
Inflammatory bowel disease is a group of chronic inflammatory conditions affecting gastrointestinal tract. Lots of genes have been identified resulting in susceptibility to inflammatory bowel disease. Any polymorphism leading to functional modifications in tyrosine kinase-2 may precipitate excessive immune response in the intestinal mucosa. The aim of our study is to investigate the involvement of tyrosine kinase-2 polymorphisms in the patients with inflammatory bowel disease in Turkish population.