학술논문
Evaluation of Circulating Endothelial Cells as Direct Marker of Endothelial Damage in Allo-Transplant Recipients at High Risk of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome
Document Type
Article
Author
Farina, Mirko; Scaini, Maria Chiara; Facchinetti, Antonella; Leoni, Alessandro; Bernardi, Simona; Catoni, Cristina; Morello, Enrico; Radici, Vera; Frioni, Filippo; Campodonico, Edoardo; Traverso, Ginevra; Cavallaro, Gianluca; Olivieri, Attilio; Galieni, Piero; Renzo, Nicola Di; Patriarca, Francesca; Carluccio, Paola; Skert, Cristina; Maffini, Enrico; Pellizzeri, Simone; Campisi, Giovanni; Re, Federica; Benedetti, Edoardo; Rosato, Antonio; Almici, Camillo; Chiusolo, Patrizia; Peccatori, Jacopo; Malagola, Michele; Poggiana, Cristina; Russo, Domenico
Source
Transplantation and Cellular Therapy; 20240101, Issue: Preprints
Subject
Language
ISSN
26666375; 26666367
Abstract
•Measurement of circulating endothelial cell (CEC) level is a valuable and direct tool for diagnosing SOS/VOD after allo-HCT.•Preconditioning CEC level can predict the development of SOS/VOD.•Combining CEC level with bilirubin level and use of haploidentical donor may help predict SOS/VOD.•Increased CEC levels can aid SOS/VOD diagnosis, especially of late-onset VOD.•CEC kinetics may assist in refining defibrotide treatment strategies.