학술논문
Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics
Document Type
Article
Source
Molecular Biology of the Cell; July 2014, Vol. 25 Issue: 14 p2152-2160, 9p
Subject
Language
ISSN
10591524; 19394586
Abstract
This study shows that capping protein (CP) is essential for mammalian cell migration in vitro and in vivo. The authors also show that CP is present in filopodia of multiple cell types and that it regulates filopodial structure and function. Thus CP function in both lamellipodia and filopodia may contribute to efficient migration.