학술논문
Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial
Document Type
Article
Author
Jochmans, Ina; Brat, Aukje; Davies, Lucy; Hofker, H Sijbrand; van de Leemkolk, Fenna E M; Leuvenink, Henri G D; Knight, Simon R; Pirenne, Jacques; Ploeg, Rutger J; Abramowicz, Daniel; Banga, Neal; Bemelman, Frederike J; Betjes, Michiel GH; Burns, Richéal; Chiocchia, Virginia; Christiaans, Maarten HL; Darius, Tom; de Jonge, Jeroen; de Vries, Aiko PJ; Detry, Olivier; Hilbrands, Luuk B; Hofker, H Sijbrand; Hoksbergen, Arjan WJ; Huurman, Volkert AL; Idu, Mirza M; Jacobs-Tulleneers-Thevissen, Daniel; Jochmans, Ina; Kaisar, Maria; Kanaan, Nada; Kimenai, Diederik; Kuypers, Dirk; Le Moine, Alain; Marshall, Carl; Meurisse, Nicolas; Mikhalski, Dimitri; Moers, Cyril; Monbaliu, Diethard; Nijboer, Willemijn N; Nurmohamed, S Azam; O'Callaghan, John; Papalois, Vassilios; Pipeleers, Lissa; Poyck, Paul PC; Quiroga, Isabel; Randon, Caren; Schurink, Geert W; Seelen, Marc; Szabo, Laszlo; Toorop, Raechel J; van de Poll, Marcel CG; van der Jagt, Michel FP; Van Laecke, Steven; van Zuilen, Arjan D; Weekers, Laurent; Ysebaert, Dirk
Source
The Lancet; November 2020, Vol. 396 Issue: 10263 p1653-1662, 10p
Subject
Language
ISSN
01406736; 1474547X
Abstract
Deceased donor kidneys are preserved in cold hypoxic conditions. Providing oxygen during preservation might improve post-transplant outcomes, particularly for kidneys subjected to greater degrees of preservation injury. This study aimed to investigate whether supplemental oxygen during hypothermic machine perfusion (HMP) could improve the outcome of kidneys donated after circulatory death.