학술논문
Checkpoint Inhibitor Monotherapy in Potentially Trial-Eligible or Trial-Ineligible Patients With Metastatic NSCLC in the German Prospective CRISP Registry Real-World Cohort (AIO-TRK-0315)
Document Type
Article
Author
Griesinger, Frank; Eberhardt, Wilfried E.E.; Brueckl, Wolfgang M.; Hummel, Horst-Dieter; Jaeschke, Bastian; Kern, Jens; Wesseler, Claas; Jänicke, Martina; Fleitz, Annette; Zacharias, Stefan; Hipper, Annette; Groth, Annika; Weichert, Wilko; Dörfel, Steffen; Petersen, Volker; Schröder, Jan; Wilke, Jochen; Sebastian, Martin; Thomas, Michael; Ababei, Juliana; Alt, Jürgen; Ammon, Andreas; Anhuf, Jürgen; Azeh, Ivo; Bauer, Stefan; Behringer, Dirk; Berger, Winfried; Bernhardt, Christiane; Bertram, Mathias; Boesche, Michael; Bohnet, Sabine; Bruch, Harald-Robert; Brückl, Wolfgang; Burkhard-Meier, Ulrike; Christopoulos, Petros; Däßler, Klaus-Ulrich; de Wit, Maike; Dechow, Tobias; Depenbusch, Reinhard; Dietze, Lutz; Dommach, Markus; Dörfel, Steffen; Eberhardt, Wilfried; Elender, Corinna; Elsel, Wolfgang; Emde, Till-Oliver; Faehling, Martin; Fietz, Thomas; Fischer, Jürgen R.; Flieger, Dimitri; Freidt, Anke; Freier, Werner; Frenzel, Christian; Fuchs, Florian; Fuchs, Roswitha; Gaska, Tobias; Gleiber, Wolfgang; Grah, Christian; Griesinger, Frank; Grohé, Christian; Groschek, Matthias; Güldenzoph, Björn; Günther, Andreas; Haas, Siegfried; Hackenthal, Matthias; Hagen, Volker; Hahn, Lars; Hannig Carla, Verena; Hansen, Richard; Harich, Hanns-Detlev; Heilmann, Monika; Heinrich, Kathrin; Hering-Schubert, Christiane; Heßling, Jörg; Hoffknecht, Petra; Hortig, Patricia; Hübner, Gerdt; Hummel, Horst-Dieter; Hutzschenreuter, Ulrich; Illmer, Thomas; Innig, Georg; Jaeschke, Bastian; Junghanß, Christian; Kaiser, Ulrich; Kamal, Haytham; Kambartel, Kato; Kern, Jens; Kimmich, Martin; Kingreen, Dorothea; Kirchen, Heinz; Klausmann, Martine; Klein, Ortwin; Kokowski, Konrad; Körber, Wolfgang; Kortsik, Cornelius; Koschel, Dirk; Krämer, Benoit; Krammer-Steiner, Beate; Laack, Eckart; Lamberti, Christof; Leistner, Rumo David; Losem, Christoph; Lück, Andreas; Maintz, Christoph; Martin, Kerstin; Medgenberg, Dirk; Metzenmacher, Martin; Meyer zum Büschenfelde, Christian; Meyn, Philipp; Moorahrend, Enno; Müller, Annette; Müller, Lothar; Neise, Michael; Nückel, Holger; Nusch, Arnd; Overbeck, Tobias; Pelz, Henning; Petersen, Volker; Peuser, Bettina; Plath, Margarete; Randerath, Winfried J.; Rauh, Jacqueline; Reck, Martin; Reichert, Dietmar; Reinmuth, Niels; Reiser, Marcel; Repp, Roland; Reschke, Daniel; Rittmeyer, Achim; Rodemer, Yolanda; Sackmann, Sandra; Sadjadian, Parvis; Sandner, Reiner; Sauer, Annette; Schäfer, Harald; Schaudt, Christoph; Schlag, Rudolf; Schmidt, Burkhard; Schmitz, Stephan; Schröder, Jan; Schroeder, Michael; Schulze, Mathias; Schumann, Christian; Schütte, Wolfgang; Schwaiblmair, Martin; Schwindt Peter, Florian; Sebastian, Martin; Seese, Bernd; Seipelt, Gernot; Sorgenfrei, Thomas; Steiff, Johannes; Steiniger, Heike; Trarbach, Tanja; Tufman, Amanda; Uhlig, Jens; Vehling-Kaiser, Ursula; von der Heyde, Eyck; von Verschuer, Ulla; Waller, Cornelius; Wehler, Thomas; Weißenborn, Georg; Weißinger, Florian; Wermke, Martin; Wesseler, Claas; Wiegand, Jörg; Wilhelm, Stefan; Wilke, Jochen; Zahn, Mark-Oliver; Zaiss, Matthias; Zeth, Matthias
Source
JTO Clinical and Research Reports; April 2024, Vol. 5 Issue: 4
Subject
Language
ISSN
26663643
Abstract
Patients with metastatic NSCLC (mNSCLC) treated with immune checkpoint inhibitors in clinical practice may often not meet the strict inclusion criteria of clinical trials. Our aim was to assess the trial eligibility of patients with mNSCLC treated with pembrolizumab monotherapy in real-world and to compare the outcome of “trial-ineligible” and “potentially trial-eligible” patients.