학술논문
Rates of viral suppression in a cohort of people with stable HIV from two community models of ART delivery versus facility-based HIV care in Lusaka, Zambia: a cluster-randomised, non-inferiority trial nested in the HPTN 071 (PopART) trial
Document Type
Article
Author
Limbada, Mohammed; Macleod, David; Situmbeko, Vasty; Muhau, Ellen; Shibwela, Osborn; Chiti, Bwalya; Floyd, Sian; Schaap, Albertus J; Hayes, Richard; Fidler, Sarah; Ayles, Helen; Hayes, Richard; Fidler, Sarah; Beyers, Nulda; Ayles, Helen; Bock, Peter; El-Sadr, Wafaa; Cohen, Myron; Bond, Virginia; Eshleman, Susan; Donnell, Deborah; Floyd, Sian; Hoddinott, Graeme; Donnell, Deborah; Macleod, Dave; Burns, David; Fraser, Christopher; Emel, Lynda; Noble, Heather; Cori, Anne; Sista, Niru; Griffith, Sam; Moore, Ayana; Headen, Tanette; White, Rhonda; Miller, Eric; Hargreaves, James; Hauck, Katharina; Thomas, Ranjeeta; Limbada, Mohammed; Bwalya, Justin; Mwinga, Alwyn; Pickles, Michael; Sabapathy, Kalpana; Schaap, Albertus J; Phiri, Mwelwa; Chiti, Bwalya; Mwenge, Lawrence; Dunbar, Rory; Shanaube, Kwame; Yang, Blia; Simwinga, Musonda; Smith, Peter C; Mandla, Nomtha; Makola, Nozizwe; Van Deventer, Anneen; Sakala, Ephraim; Jennings, Karen; Kosloff, Barry; Kanema, Sarah; Probert, Will; Kumar, Ramya; Silumesi, Andrew; Skalland, Tim; Yuhas, Krista
Source
The Lancet HIV; January 2022, Vol. 9 Issue: 1 pe13-e23, 11p
Subject
Language
ISSN
24054704; 23523018
Abstract
Non-facility-based antiretroviral therapy (ART) delivery for people with stable HIV might increase sustainable ART coverage in low-income and middle-income countries. Within the HPTN 071 (PopART) trial, two interventions, home-based delivery (HBD) and adherence clubs (AC), which included groups of 15–30 participants who met at a communal venue, were compared with standard of care (SoC). In this trial we looked at the effectiveness and feasibility of these alternative models of care. Specifically, this trial aimed to assess whether these models of care had similar virological suppression to that of SoC 12 months after enrolment.