학술논문
Safety Test and Field Study of an Inactivated Oil-Adjuvanted H5NI Avian Influenza Vaccine.
Document Type
Article
Author
Source
Journal of Veterinary Medical Science; Nov2010, Vol. 72 Issue 11, p1455-1463, 9p, 12 Charts, 5 Graphs
Subject
Language
ISSN
09167250
Abstract
The article examines the safety and efficacy of an inactivated oil-adjuvanted avian influenza vaccine using an apathogenic H5N1 strain. Methods and materials used in this study are detailed. The results show high antibody response in chickens inoculated with oil-adjuvanted vaccines but presented adverse reactions such as residual oil and inflammatory cell infiltration. The safety net shows no abnormalities induced by intramuscular vaccine injection with one dose. In conclusion, the vaccine exhibited no adverse effects in laboratories and chicken farms.