학술논문

Belgian 2024 guidance on the use of pre-exposure prophylaxis
Document Type
Article
Source
Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine; March 2024, Vol. 79 Issue: 2 p121-129, 9p
Subject
Language
ISSN
17843286; 22953337
Abstract
ABSTRACTObjectivesWe aimed to develop a guidance on the use of pre-exposure prophylaxis (PrEP) for HIV tailored to the Belgian context.MethodsDifferent aspects of PrEP care were judged by an expert group of nine Belgian clinicians, seeking consensus for areas of controversies.ResultsPrEP should be considered in HIV negative patients at high risk of acquiring HIV. Currently, only oral tenofovir/emtricitabine is available in Belgium for PrEP, which can be used daily, or also event-driven in cisgender men and trans women who are not taking exogenous estradiol-based hormones. Personal counselling directed at medication adherence and sexual health should have a central role in PrEP care. At the initial assessment clinicians should give attention to symptoms of an acute HIV infection, the patients’ immunization status and renal function. A regular follow-up must be set up to diagnose HIV seroconversion, treat sexually transmitted infections, and manage side effects of PrEP.ConclusionThe Belgian guidance on the use of PrEP provides a point of reference for standard PrEP care in Belgium and will be periodically updated.