학술논문
Performance of the 47-Kilodalton Membrane Protein versus DNA Polymerase I Genes for Detection of Treponema pallidumby PCR in Ulcers
Document Type
Article
Author
Gayet-Ageron, Angèle; Laurent, Frédéric; Schrenzel, Jacques; Charton, Béatrice; Jimenez-Getaz, Gisela; Tangomo, Manuela; Ferry, Tristan; Sednaoui, Patrice; Lautenschlager, Stephan; Toutous-Trellu, Laurence; Martinez de Tejada, Begoña; Cavassini, Matthias; Emonet, Stéphane; Perneger, Thomas; Salord, Hélène
Source
Journal of Clinical Microbiology; December 2014, Vol. 53 Issue: 3 p976-980, 5p
Subject
Language
ISSN
00951137; 1098660X
Abstract
ABSTRACTTreponema pallidumPCR (Tp-PCR) is a direct diagnostic method for primary and secondary syphilis, but there is no recommendation regarding the best choice of target gene. In this study, we sequentially tested 272 specimens from patients with sexually transmitted ulcers using Tp-PCR targeting the tpp47and then polAgenes. The two methods showed similar accuracies and an almost-perfect agreement.