학술논문
Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients
Document Type
Article
Author
Source
Arthritis Research & Therapy (formerly Arthritis Research); June 2010, Vol. 12 Issue: 3 pR108-R108, 1p
Subject
Language
ISSN
14786354; 14786362
Abstract
Systemic lupus erythematosus (SLE) is characterized by B cell hyper-activation and auto-reactivity resulting in pathogenic auto-antibody generation. The phenotypic analysis of blood B cell subsets can be used to understand these alterations.