학술논문

Choriocapillaris evaluation in choroideremia using optical coherence tomography angiography
Document Type
Article
Source
Biomedical Optics Express; January 2017, Vol. 8 Issue: 1 p48-56, 9p
Subject
Language
ISSN
21567085
Abstract
The choriocapillaris plays an important role in supporting the metabolic demands of the retina. Studies of the choriocapillaris in disease states with optical coherence tomography angiography (OCTA) have proven insightful. However, image artifacts complicate the identification and quantification of the choriocapillaris in degenerative diseases such as choroideremia. Here, we demonstrate a supervised machine learning approach to detect intact choriocapillaris based on training with results from an expert grader. We trained a random forest classifier to evaluate en face structural OCT and OCTA information along with spatial image features. Evaluation of the trained classifier using previously unseen data showed good agreement with manual grading.