학술논문

Determination of the Stereochemistry of Hydride Transfer from NADPH to FAD Catalyzed by VlmR, a Flavin Reductase from the Valanimycin Biosynthetic Pathway
Document Type
Article
Source
Organic Letters; April 2001, Vol. 3 Issue: 8 p1117-1119, 3p
Subject
Language
ISSN
15237060; 15237052
Abstract
The stereospecificity of hydride transfer from NADPH to FAD catalyzed by VlmR, a flavin reductase from the valanimycin biosynthetic pathway has been determined. By using stereospecifically deuterated NADPH, it has been shown that the 4-pro R hydrogen of NADPH is transferred.