학술논문
A putative int domain for mouse mammary tumor virus on mouse chromosome 7 is a 5' extension of int-2
Document Type
Article
Author
Source
The Journal of Virology; March 1989, Vol. 63 Issue: 3 p1448-1450, 3p
Subject
Language
ISSN
0022538X; 10985514
Abstract
We extended the physical map of the mouse int-2 locus by demonstrating that the site of insertion for mouse mammary tumor virus DNA in plaque-type mammary tumors of GR mice is directly linked to int-2. An additional example of proviral integration is described in which a provirus in a presumed enhancer-insertion mode 15 kilobases upstream of the int-2 promoters is capable of activating expression of the gene at levels typical of other virally induced mammary tumors.