학술논문
Long-term clinical effectiveness of continuous positive airway pressure therapy versus non-invasive ventilation therapy in patients with obesity hypoventilation syndrome: a multicentre, open-label, randomised controlled trial
Document Type
Article
Author
Masa, Juan F; Mokhlesi, Babak; Benítez, Iván; Gomez de Terreros, Francisco Javier; Sánchez-Quiroga, Maria Ángeles; Romero, Auxiliadora; Caballero-Eraso, Candela; Terán-Santos, Joaquin; Alonso-Álvarez, Maria Luz; Troncoso, Maria F; González, Mónica; López-Martín, Soledad; Marin, José M; Martí, Sergi; Díaz-Cambriles, Trinidad; Chiner, Eusebi; Egea, Carlos; Barca, Javier; Vázquez-Polo, Francisco-José; Negrín, Miguel A; Martel-Escobar, María; Barbe, Ferran; Corral, Jaime; Fernández, Galo; Ordax-Carbajo, Estrella; González-Mangado, Nicolás; Gómez-García, Teresa; Martínez-Martínez, María-Ángeles; Ojeda-Castillejo, Elena; López Padilla, Daniel; Carrizo, Santiago J; Gallego, Begoña; Pallero, Mercedes; Romero, Odile; Ramón, María Antonia; Arias, Eva; Muñoz-Méndez, Jesús; Senent, Cristina; Sancho-Chust, José N.; Navarro Soriano, Nieves Belén; Barrot, Emilia; Benítez, José M.; Sánchez-Gómez, Jesús; Golpe, Rafael; Santiago-Recuerda, Ana; Gómez, Silvia; Bengoa, Mónica
Source
The Lancet; April-May 2019, Vol. 393 Issue: 10182 p1721-1732, 12p
Subject
Language
ISSN
01406736; 1474547X
Abstract
Obesity hypoventilation syndrome is commonly treated with continuous positive airway pressure or non-invasive ventilation during sleep. Non-invasive ventilation is more complex and costly than continuous positive airway pressure but might be advantageous because it provides ventilatory support. To date there have been no long-term trials comparing these treatment modalities. We therefore aimed to determine the long-term comparative effectiveness of both treatment modalities.