학술논문
Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial
Document Type
Article
Author
Ueki, Kohjiro; Sasako, Takayoshi; Okazaki, Yukiko; Kato, Masayuki; Okahata, Sumie; Katsuyama, Hisayuki; Haraguchi, Mikiko; Morita, Ai; Ohashi, Ken; Hara, Kazuo; Morise, Atsushi; Izumi, Kazuo; Ishizuka, Naoki; Ohashi, Yasuo; Noda, Mitsuhiko; Kadowaki, Takashi; Haneda, Masakazu; Iwashima, Yasunori; Suda, Toshihiro; Tamasawa, Naoki; Daimon, Makoto; Satoh, Jo; Takebe, Noriko; Ishigaki, Yasushi; Watanabe, Tsuyoshi; Satoh, Hiroaki; Kasai, Kikuo; Aso, Yoshimasa; Ishibashi, Shun; Katayama, Shigehiro; Ishikawa, San-e; Kakei, Masafumi; Namai, Kazuyuki; Hashimoto, Naotake; Suzuki, Yoshifumi; Onishi, Shunichiro; Yokote, Koutaro; Matsuda, Masafumi; Masuzawa, Masahiro; Hayashi, Yoichi; Saito, Satoshi; Ogihara, Norikazu; Ishihara, Hisamitsu; Tajima, Naoko; Utsunomiya, Kazunori; Shimada, Akira; Itoh, Hiroshi; Kawamori, Ryuzo; Watada, Hirotaka; Hayashi, Michio; Mori, Yasumichi; Shiba, Teruo; Isogawa, Akihiro; Sakura, Hiroshi; Odawara, Masato; Tobe, Kazuyuki; Tsukamoto, Kazuhisa; Yamauchi, Toshimasa; Teramoto, Tamio; Hirata, Yukio; Uchimura, Isao; Ogawa, Yoshihiro; Yoshino, Gen; Hirose, Takahisa; Kajio, Hiroshi; Atsumi, Yoshihito; Shimada, Akira; Oikawa, Yoichi; Araki, Atsushi; Ueki, Akio; Ohno, Atsushi; Kitaoka, Masafumi; Fujita, Yoshikuni; Moriya, Tatsumi; Tojo, Taiki; Shichiri, Masayoshi; Suzuki, Daisuke; Toyoda, Masao; Hamano, Kumiko; Komi, Rieko; Terauchi, Yasuo; Kuzuya, Nobuaki; Yamada, Masayo; Takamura, Toshinari; Imura, Mitsuo; Tanaka, Hiroshi; Hayashi, Masayuki; Kato, Yasuhisa; Itoh, Mitsuyasu; Suzuki, Atsushi; Nakayama, Mikihiro; Sano, Takahisa; Nakashima, Eitaro; Sumida, Yasuhiro; Yano, Yutaka; Tanaka, Tsuyoshi; Murata, Kazuya; Kashiwagi, Atsunori; Maegawa, Hiroshi; Kono, Shigeo; Inagaki, Nobuya; Kosugi, Keisuke; Yasuda, Tetsuyuki; Yoshimasa, Yasunao; Kishimoto, Ichiro; Sato, Toshihiko; Hosoi, Masayuki; Yamasaki, Tomoyuki; Matsuhisa, Munehide; Shimomura, Iichiro; Taniguchi, Ataru; Kuroe, Akira; Kurose, Takeshi; Ohara, Takeshi; Sakaguchi, Kazuhiko; Namba, Mitsuyoshi; Kaku, Kohei; Fujiwara, Masazumi; Shimizu, Ikki; Ono, Keizo; Ebisui, Osamu; Tanizawa, Yukio; Okada, Yosuke; Natori, Shoichi; Kodera, Takehiko; Sato, Naoichi; Ide, Makoto; Yamada, Kentaro; Umeda, Fumio; Natori, Shoichi; Eto, Tomoaki; Mimura, Kazuo; Hiramatsu, Shinsuke; Inoue, Tomoaki; Takei, Ryoko; Ogo, Atsushi; Eguchi, Katsumi; Kawasaki, Eiji; Koide, Yuji; Araki, Eiichi; Jinnouchi, Hideaki; Yamamoto, Hiroaki; Motoyoshi, Mitsutaka; Hiyoshi, Toru; Tanaka, Yasushi; Momoki, Tadahisa; Sato, Koichiro; Yoneyama, Akihiko; Ito, Kenichi; Sobajima, Hiroshi; Ikegami, Hiroshi; Ikeda, Masaki; Ikeda, Hiroki; Takahashi, Kenji; Makino, Hirofumi; Ueda, Yasuo; Nakazato, Masamitsu
Source
The Lancet Diabetes & Endocrinology; December 2017, Vol. 5 Issue: 12 p951-964, 14p
Subject
Language
ISSN
22138587; 22138595
Abstract
Limited evidence suggests that multifactorial interventions for control of glucose, blood pressure, and lipids reduce macrovascular complications and mortality in patients with type 2 diabetes. However, safe and effective treatment targets for these risk factors have not been determined for such interventions.