부산대학교 도서관

This study aimed to assess the effects of a Lactobacillus helveticusATCC 15009-derived postbiotic in mitigating experimental SalmonellaGallinarum infection. For this purpose, a sample of Lactobacillussp. was inoculated in 2 different media, each containing different postbiotics (sensitized and nonsensitized). Both inocula had their antagonistic effect over S.Gallinarum tested through the spot-on-the-lawn method. It revealed that the sensitized postbiotic had a higher action potential over Lactobacillussp. than the nonsensitized one (P< 0.05). Then, 48 day of hatch chicks were divided into 4 groups: A = Lactobacillussp. (109CFU/mL) inoculum on the 18th day; B = Lactobacillussp. (109CFU/mL) inoculum on the 18th day and postbiotic inoculum on the 19th day; C = postbiotic inoculum on the 19th day; and D = sterile saline inoculum on 18th and 19th days. On the 21st day, all chicks were infected with S. Gallinarum (109CFU/mL). On the 23rd day, the animals were euthanized by cervical dislocation, and the ceca and liver were aseptically removed. Bacterial count of S.Gallinarum with serial decimal dilution was performed with these organs. It revealed that the prophylactic treatment with the postbiotic that modulates the intestinal microbiota was as efficient as the probiotic administration in reducing S. Gallinarum in the cecum and liver of chicks (P< 0.05). These data point to a new range of alternatives for preventing S. Gallinarum, which might help the poultry industry produce safer food for human consumption.