학술논문
Epigenetic Age Acceleration in Adolescence Associates With BMI, Inflammation, and Risk Score for Middle Age Cardiovascular Disease.
Document Type
Article
Author
Source
The Journal of Clinical Endocrinology & Metabolism; July 2019, Vol. 104 Issue: 7 p3012-3024, 13p
Subject
Language
ISSN
0021972X; 19457197
Abstract
"Accelerated aging," assessed by adult DNA methylation, predicts cardiovascular disease (CVD). Adolescent accelerated aging might predict CVD earlier. We investigated whether epigenetic age acceleration (assessed age, 17 years) was associated with adiposity/CVD risk measured (ages 17, 20, and 22 years) and projected CVD by middle age.