학술논문
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidiumin mice by inhibiting parasite phenylalanyl-tRNA synthetase
Document Type
Article
Author
Vinayak, Sumiti; Jumani, Rajiv S.; Miller, Peter; Hasan, Muhammad M.; McLeod, Briana I.; Tandel, Jayesh; Stebbins, Erin E.; Teixeira, Jose E.; Borrel, Julien; Gonse, Arthur; Zhang, Mingliang; Yu, Xianshui; Wernimont, Amy; Walpole, Chris; Eckley, Sean; Love, Melissa S.; McNamara, Case W.; Sharma, Manmohan; Sharma, Amit; Scherer, Christina A.; Kato, Nobutaka; Schreiber, Stuart L.; Melillo, Bruno; Striepen, Boris; Huston, Christopher D.; Comer, Eamon
Source
Science Translational Medicine; September 2020, Vol. 12 Issue: 563
Subject
Language
ISSN
19466234; 19466242
Abstract
Bicyclic azetidines potently inhibit Cryptosporidiumin vivo by targeting phenylalanyl-tRNA synthetase.