학술논문
Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study
Document Type
Article
Author
Närhi, Fiina; Moonesinghe, S Ramani; Shenkin, Susan D; Drake, Thomas M; Mulholland, Rachel H; Donegan, Cara; Dunning, Jake; Fairfield, Cameron J; Girvan, Michelle; Hardwick, Hayley E; Ho, Antonia; Leeming, Gary; Nguyen-Van-Tam, Jonathan S; Pius, Riinu; Russell, Clark D; Shaw, Catherine A; Spencer, Rebecca G; Turtle, Lance; Openshaw, Peter J M; Baillie, J Kenneth; Harrison, Ewen M; Semple, Malcolm G; Docherty, Annemarie B; Baillie, J Kenneth; Semple, Malcolm G; Openshaw, Peter JM; Carson, Gail; Alex, Beatrice; Andrikopoulos, Petros; Bach, Benjamin; Barclay, Wendy S; Bogaert, Debby; Chand, Meera; Chechi, Kanta; Cooke, Graham S; da Silva Filipe, Ana; de Silva, Thushan; Docherty, Annemarie B; dos Santos Correia, Gon¸alo; Dumas, Marc-Emmanuel; Dunning, Jake; Fletcher, Tom; Green, Christopher A; Greenhalf, William; Griffin, Julian; Gupta, Rishi K; Harrison, Ewen M; Hiscox, Julian A; Ho, Antonia YW; Horby, Peter W; Ijaz, Samreen; Khoo, Say; Klenerman, Paul; Law, Andrew; Lewis, Matthew; Liggi, Sonia; Lim, Wei Shen; Maslen, Lynn; Mentzer, Alexander J; Merson, Laura; Meynert, Alison M; Moore, Shona C; Noursadeghi, Mahdad; Olanipekun, Michael; Osagie, Anthonia; Palmarini, Massimo; Palmieri, Carlo; Paxton, William A; Pollakis, Georgios; Price, Nicholas; Rambaut, Andrew; Robertson, David L; Russell, Clark D; Sancho-Shimizu, Vanessa; Sands, Caroline; Scott, Janet T; Sigfrid, Louise; Solomon, Tom; Sriskandan, Shiranee; Stuart, David; Summers, Charlotte; Swann, Olivia V; Takats, Zoltan; Takis, Panteleimon; Tedder, Richard S; Thompson, AA Roger; Thomson, Emma C; Thwaites, Ryan S; Turtle, Lance CW; Zambon, Maria; Hardwick, Hayley; Donohue, Chloe; Griffiths, Fiona; Oosthuyzen, Wilna; Donegan, Cara; Spencer, Rebecca G; Norman, Lisa; Pius, Riinu; Drake, Thomas M; Fairfield, Cameron J; Knight, Stephen R; Mclean, Kenneth A; Murphy, Derek; Shaw, Catherine A; Dalton, Jo; Girvan, Michelle; Saviciute, Egle; Roberts, Stephanie; Harrison, Janet; Marsh, Laura; Connor, Marie; Halpin, Sophie; Jackson, Clare; Gamble, Carrol; Plotkin, Daniel; Lee, James; Leeming, Gary; Law, Andrew; Wham, Murray; Clohisey, Sara; Hendry, Ross; Scott-Brown, James; Shaw, Victoria; McDonald, Sarah E; Keating, Seán; Ahmed, Katie A.; Armstrong, Jane A; Ashworth, Milton; Asiimwe, Innocent G; Bakshi, Siddharth; Barlow, Samantha L; Booth, Laura; Brennan, Benjamin; Bullock, Katie; Catterall, Benjamin WA; Clark, Jordan J; Clarke, Emily A; Cole, Sarah; Cooper, Louise; Cox, Helen; Davis, Christopher; Dincarslan, Oslem; Dunn, Chris; Dyer, Philip; Elliott, Angela; Evans, Anthony; Finch, Lorna; Fisher, Lewis WS; Foster, Terry; Garcia-Dorival, Isabel; Gunning, Philip; Hartley, Catherine; Jensen, Rebecca L; Jones, Christopher B; Jones, Trevor R; Khandaker, Shadia; King, Katharine; Kiy, Robyn T.; Koukorava, Chrysa; Lake, Annette; Lant, Suzannah; Latawiec, Diane; Lavelle-Langham, Lara; Lefteri, Daniella; Lett, Lauren; Livoti, Lucia A; Mancini, Maria; McDonald, Sarah; McEvoy, Laurence; McLauchlan, John; Metelmann, Soeren; Miah, Nahida S; Middleton, Joanna; Mitchell, Joyce; Moore, Shona C; Murphy, Ellen G; Penrice-Randal, Rebekah; Pilgrim, Jack; Prince, Tessa; Reynolds, Will; Ridley, P. Matthew; Sales, Debby; Shaw, Victoria E; Shears, Rebecca K; Small, Benjamin; Subramaniam, Krishanthi S; Szemiel, Agnieska; Taggart, Aislynn; Tanianis-Hughes, Jolanta; Thomas, Jordan; Trochu, Erwan; van Tonder, Libby; Wilcock, Eve; Zhang, J. Eunice; Flaherty, Lisa; Maziere, Nicole; Cass, Emily; Doce Carracedo, Alejandra; Carlucci, Nicola; Holmes, Anthony; Massey, Hannah; Murphy, Lee; McCafferty, Sarah; Clark, Richard; Fawkes, Angie; Morrice, Kirstie; Maclean, Alan; Wrobel, Nicola; Donelly, Lorna; Coutts, Audrey; Hafezi, Katarzyna; MacGillivray, Louise; Gilchrist, Tammy; Adeniji, Kayode; Agranoff, Daniel; Agwuh, Ken; Ail, Dhiraj; Aldera, Erin L.; Alegria, Ana; Allen, Sam; Angus, Brian; Ashish, Abdul; Atkinson, Dougal; Bari, Shahedal; Barlow, Gavin; Barnass, Stella; Barrett, Nicholas; Bassford, Christopher; Basude, Sneha; Baxter, David; Beadsworth, Michael; Bernatoniene, Jolanta; Berridge, John; Berry, Colin; Best, Nicola; Bothma, Pieter; Chadwick, David; Brittain-Long, Robin; Bulteel, Naomi; Burden, Tom; Burtenshaw, Andrew; Caruth, Vikki; Chadwick, David; Chambler, Duncan; Chee, Nigel; Child, Jenny; Chukkambotla, Srikanth; Clark, Tom; Collini, Paul; Cosgrove, Catherine; Cupitt, Jason; Cutino-Moguel, Maria-Teresa; Dark, Paul; Dawson, Chris; Dervisevic, Samir; Donnison, Phil; Douthwaite, Sam; Drummond, Andrew; DuRand, Ingrid; Dushianthan, Ahilanadan; Dyer, Tristan; Evans, Cariad; Eziefula, Chi; Fegan, Chrisopher; Finn, Adam; Fullerton, Duncan; Garg, Sanjeev; Garg, Sanjeev; Garg, Atul; Gkrania-Klotsas, Effrossyni; Godden, Jo; Goldsmith, Arthur; Graham, Clive; Hardy, Elaine; Hartshorn, Stuart; Harvey, Daniel; Havalda, Peter; Hawcutt, Daniel B; Hobrok, Maria; Hodgson, Luke; Hormis, Anil; Jacobs, Michael; Jain, Susan; Jennings, Paul; Kaliappan, Agilan; Kasipandian, Vidya; Kegg, Stephen; Kelsey, Michael; Kendall, Jason; Kerrison, Caroline; Kerslake, Ian; Koch, Oliver; Koduri, Gouri; Koshy, George; Laha, Shondipon; Laird, Steven; Larkin, Susan; Leiner, Tamas; Lillie, Patrick; Limb, James; Linnett, Vanessa; Little, Jeff; Lyttle, Mark; MacMahon, Michael; MacNaughton, Emily; Mankregod, Ravish; Masson, Huw; Matovu, Elijah; McCullough, Katherine; McEwen, Ruth; Meda, Manjula; Mills, Gary; Minton, Jane; Mirfenderesky, Mariyam; Mohandas, Kavya; Mok, Quen; Moon, James; Moore, Elinoor; Morgan, Patrick; Morris, Craig; Mortimore, Katherine; Moses, Samuel; Mpenge, Mbiye; Mulla, Rohinton; Murphy, Michael; Nagel, Megan; Nagarajan, Thapas; Nelson, Mark; Norris, Lillian; O'Shea, Matthew K.; Otahal, Igor; Ostermann, Marlies; Pais, Mark; Palmieri, Carlo; Panchatsharam, Selva; Papakonstantinou, Danai; Paraiso, Hassan; Patel, Brij; Pattison, Natalie; Pepperell, Justin; Peters, Mark; Phull, Mandeep; Pintus, Stefania; Singh Pooni, Jagtur; Planche, Tim; Post, Frank; Price, David; Prout, Rachel; Rae, Nikolas; Reschreiter, Henrik; Reynolds, Tim; Richardson, Neil; Roberts, Mark; Roberts, Devender; Rose, Alistair; Rousseau, Guy; Ruge, Bobby; Ryan, Brendan; Saluja, Taranprit; Schmid, Matthias; Shah, Aarti; Shanmuga, Prad; Sharma, Anil; Shawcross, Anna; Sizer, Jeremy; Shankar-Hari, Manu; Smith, Richard; Snelson, Catherine; Spittle, Nick; Staines, Nikki; Stambach, Tom; Stewart, Richard; Subudhi, Pradeep; Szakmany, Tamas; Tatham, Kate; Thomas, Jo; Thompson, Chris; Thompson, Robert; Tridente, Ascanio; Tupper-Carey, Darell; Twagira, Mary; Vallotton, Nick; Vancheeswaran, Rama; Vincent-Smith, Lisa; Visuvanathan, Shico; Vuylsteke, Alan; Waddy, Sam; Wake, Rachel; Walden, Andrew; Welters, Ingeborg; Whitehouse, Tony; Whittaker, Paul; Whittington, Ashley; Papineni, Padmasayee; Wijesinghe, Meme; Williams, Martin; Wilson, Lawrence; Sarah, Sarah; Winchester, Stephen; Wiselka, Martin; Wolverson, Adam; Wootton, Daniel G; Workman, Andrew; Yates, Bryan; Young, Peter
Source
The Lancet Digital Health; April 2022, Vol. 4 Issue: 4 pe220-e234, 15p
Subject
Language
ISSN
25897500
Abstract
Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY trial publication on June 16, 2020, and to identify discrepancies in care.